March Madness is heading to the Sweet 16 without a handful of top teams. Two No. 1 seeds, Kansas and Purdue, No. 2 seed Arizona and No. 4 seed Virginia are all gone — and gone with them are millions of busted brackets.

It's been tough sledding for the bluebloods, too: Besides Kansas, Kentucky, Duke and Indiana are all heading home. UCLA's drive for a 12th national title remains alive.

Here is what to know with the regional semifinals up next at the NCAA Tournament:

TOP SEEDS

The top four seeds in the tournament were given to Alabama, Houston, Kansas and Purdue. Each had its share of headaches to set up what is proving to be a chaotic tournament. The Boilermakers were the first to fall, ousted in a first-round stunner, and the Jayhawks followed the very next day.

EAST REGION: The Boilermakers got a top seed for the fourth time, but Purdue was dumped by Fairleigh Dickinson in a near-historic upset. and the 2-seed, Marquette, is also gone. Up next: No. 9 seed FAU vs. No. 4 seed Tennessee and No. 3 seed Kansas State vs. No. 7 seed Michigan State, whose coach Tom Izzo is heading to his 15th regional.

SOUTH REGION: Alabama, led by coach Nate Oats in a challenging season, got a top seed for the first time behind SEC player of the year Brandon Miller, who has armed security on hand after being the subject of threats. Up next: No. 1 seed Alabama vs. No. 5 seed San Diego State and No. 6 seed Creighton vs. No. 15 seed Princeton, which is in rare territory.

MIDWEST REGION: Houston got a top seed and won its opener before a rugged victory over Auburn even with All-American Marcus Sasser hobbled by a groin injury. Up next: No. 1 seed Houston vs. No. 5 seed Miami and No. 2 seed Texas vs. No. 3 seed Xavier.

WEST REGION: Kansas, the top-seeded defending national champion that was without coach Bill Self in the tournament following a heart procedure, blew an 8-point halftime lead and lost to Arkansas. Up next: No. 2 seed UCLA vs. No. 3 Gonzaga and No. 4 seed UConn vs. No. 8 seed Arkansas.

SHINING MOMENTS

The unforgettable plays are piling up.

Princeton used a late run to earn its first NCAA Tournament win in 25 years by ousting No. 2 seed Arizona and then answered any skeptics by rolling Missouri to lock in its first Sweet 16 spot in 56 years.

Furman celebrated its first tourney appearance since 1980 with a win over No. 4 seed Virginia on a deep 3-pointer by JP Pegues with 2.4 seconds left. Then came 16-seed Fairleigh Dickinson's win over Purdue as the 22 1/2-point underdog stifled 7-4 center Zach Edey to advance and join UMBC in the record books.

All that happened before the Razorbacks and shirtless coach Eric Musselman celebrated their win over the Jayhawks.

GAMES TO WATCH

No. 4 seed Connecticut (27-8) vs. No. 8 seed Arkansas (22-13), Thursday, 7:15 p.m. ET (CBS)

The Huskies are returning to the Sweet 16 for the first time in nine years, and hoping to avoid being the next victim of Arkansas, which ousted defending champion Kansas. UConn outclassed Saint Mary’s 70-55 behind 24 points by Adama Sanogo and timely 3-point shooting.

No. 2 Kansas State (25-9) vs. No. 7 Michigan State (21-12), Thursday, 6:30 p.m. ET (TBS)

Tom Izzo is taking Michigan State to the Sweet 16 for the 15th time and first in four years after a 69-60 victory against No. 2 seed Marquette. The victory was the 16th for Izzo in the tournament against a higher seed, breaking the record he shared with recently retired Syracuse coach Jim Boeheim. At Madison Square Garden, the Spartans will face a Kansas State team that was picked to finish last in the Big 12 with a remade roster and first-year coach in Jerome Tang. The Wildcats outlasted Kentucky 75-69 behind 27 points by Markquis Nowell.

No. 5 seed San Diego State (29-6) vs. No. 1 seed Alabama (31-5), Friday, 6:30 p.m. ET (TBS)

The Aztecs are heading to the Sweet 16 for the first time since 2004 and have won 11 of their last 13. Balanced scoring carried them to a second-round victory against Furman and they’ll need more of the same against the Crimson Tide, who handily dispatched Maryland in the second round. All-America freshman Brandon Miller, who is nursing an injury, had 19 after going scoreless in the first round.

No. 3 seed Xavier (27-9) vs. No. 2 seed Texas (28-8), Friday, 9:45 p.m. ET (CBS)

The Musketeers are heading to the Sweet 16 for the first time since 2017 and will face a Longhorns team that hasn’t been there in 15 years. Xavier put on a clinic on unselfishness in the first half of its 84-73 victory against Pittsburgh, totaling 17 assists on 19 made field goals. The Longhorns made just one 3-pointer in 13 tries in their 71-66 victory against Penn State, but Dylan Disu had season-high 28-point performance.

GO DEEPER

Gun violence has cost lives and disrupted college sports all season, touching some of the top programs in college basketball, including Alabama. Coaches have been thrust into uncertain and unwelcome roles in trying to navigate the topic — as well as the fallout from the Supreme Court decision to overturn Roe vs. Wade.

On a lighter note, if you feel you know March Madness pretty well, try this 25-question trivia quiz put together by AP.

PLAYERS TO WATCH

The NCAA Tournament is filled with great players and the AP All-America team is a good place to get familiar with the names. It's also an event where guys you've never heard ofcan take a star turn. Guard play is always going to be important (see: Baylor, 2021 title winner) and there are some NBA prospects in the mix.

Bet on this, too: Some player — maybe more than one — will have a chance to join the mustachioed Doug Edert(remember Saint Peters' inspiring run last year?) and find a way to cash in on their celebrity.

HOW TO WATCH

Every game of the men’s tournament will be aired — here is a schedule — either on CBS, TBS, TNT or TruTV and their digital platforms. CBS, which also has a handy schedule that includes announcing teams, will handle the Final Four and national title game this year.

The NCAA is streaming games via its March Madness Liveoption and CBS games are being streamed on Paramount+. Fans of longtime play-by-play announcer Jim Nantz should soak up every moment: It’s his final NCAA Tournament.

BETTING GUIDE

Who's going to win the national championship? The betting favorites to reach the Final Four are (in order, as of March 19): Alabama, Houston, UConn, UCLA, Gonzaga and Texas, according to FanDuel Sportsbook.

MARCH MADNESS CALENDAR

Sweet 16 weekend will see games in New York City (East Region), Las Vegas (West), Kansas City, Missouri (Midwest), and Louisville, Kentucky (South).

Where is the Final Four? In Houston, on April 1, with the championship game on April 3. Basketball aficionados, take note: The women’s NCAA Tournament will hold its Final Four in Dallas, a four-hour drive up the road from Houston.

Can't get enough March Madness? Well, there is talk about expanding the tournament despite a host of challenges. Enjoy the 68-team version for now!

Share:
More In Sports
Need2Know: Wednesday Morning News Roundup
These are the headlines you Need2Know. * **Damage Control at the White House:** President Trump will meet with his cabinet today after widespread criticism of his comments spread following Monday's joint meeting with Russian President Vladimir Putin. To appease his base,Trump declared yesterday that he simply misspoke during the presser--but some critics find that hard to believe. * **Manafort Goes to Court:** The case against former Trump campaign manager Paul Manafort is moving forward--despite a denial of his team's request for a change of location. Manafort's team asked for the trial to be moved from Alexandria to Roanoke, believing that Alexandria's more liberal base would be less forgiving and attract more press. * **University Doctor Under Fire:** A former Ohio State University doctor is accused of molesting student athletes after complaints surfaced from several ex-wrestlers--one of whom condemned is Congressman Jim Jordan for ignoring the allegations. * **Vacancies at Comic-Con:** The 2018 Comic-Con kicks of in San Diego tonight. But some of the usual attendees will be missing: network HBO, the Avengers, X-Men and Deadpool will be among the absent guests. * **American League Still Number One:** The American league clung to its title as reigning champ after it defeated the National League for the sixth straight year during last night's MLB All-Star game. Cheddar Big News' Hena Doba gives us the details.
TaylorMade CEO: Tiger Woods Is Back 'In Great Form'
The golf superstar signed with TaylorMade back in 2017 but was out of the game that year due to a back surgery and a reckless driving incident. Since then, things have turned around for Woods. He's preparing to play in the British Open in just a few days and his "ball striking is terrific, his putting is great, and I think he’s in a great position right now to challenge,” says TaylorMade CEO David Abeles.
Need2Know: Tuesday Morning News Roundup
These are the headlines you Need2Know: Trump Faces Bipartisan Backlash Russian Woman Charged With Election Meddling Hawaii's 'Lava Bomb' Injures Tourists Deadly Fire Near Yosemite National Park Doubles
Trump and Putin Meet, Families Yet to Be Reunited at the Border, Police Protests in Chicago, and More
These are the headlines you Need2Know: *President Trump meets with Russian President Putin in Helsinki, Finland, days after the indictment of 12 Russian operatives for trying to disrupt the 2016 election. *A federal judge blasts the HHS giving them one more week to reunite 2,000 families at the border after the administration missed the initial deadline. *Protests erupted in Chicago over the weekend after a popular barber was shot and killed by the police. *Novak Djokovic and Angelique Kerber won Wimbledon titles over the weekend. And France took home the World Cup. Cheddar's Hope King gives us the details.
Trump and May to Hold Joint News Conference, Chaos Erupts in Congress, Serena Rolls Into Wimbledon Finals, and More
These are the headlines you Need2Know: *President Trump is in England preparing for a joint news conference with Theresa May. While the duo dined last night, The Sun newspaper published a sit-down interview with the president where he criticized May’s handling of Brexit. Trump warned trade deals with England could be nixed if Brexit isn’t handled properly. *FBI agent Peter Strzok was removed from working on the Hillary Clinton email probe and the Trump-Russia investigation after text messages were discovered in which he criticized the president. *Stormy Daniels made an encore appearance at the same strip club she was arrested at the night prior. *A Kansas City water park will not reopen after a 10-year-old boy died on a water slide. *Serena Williams beat Julia Görges of Germany yesterday to reach her 10th Wimbledon final. Cheddar Big News's Jill Wagner gives us the details.
Tensions Rise at NATO Summit, Stormy Daniels Arrested, Senate Votes on Tariff Resolution, and More
These are the headlines you Need2Know: * Confusion at the NATO summit after President Trump said allies will add billions of dollars to defense spending. But French president Emmanuel Macron rebuffed those claims. * Stormy Daniels was arrested after an alleged misdemeanor at a Columbus, Ohio, strip club. Her lawyer, Michael Avenatti, has also been working to reunite families at the southern border. * The U.S. Senate voted yesterday on a non-binding resolution giving it a say on what tariffs are levied and against whom. * New evidence prompted the Department of Justice reopened the case of Emmett Till, a 14-year-old boy who was killed in 1955 in Money, Miss. * John Schnatter, founder and former CEO of Papa John’s, has resigned his chairman role after a racially-charged comment on a conference call. * Americans made it to both the men’s and women’s Wimbledon semifinals, the first time since 2009. Cheddar Big News' Jill Wagner tells us the latest.
NATO Summit Kicks Off, White House Misses Immigration Deadline, Deadly Gas Explosion in Midwest, and More
These are the headlines you Need2Know: The NATO Summit got off to a heated start as President Trump already criticized member countries for not paying their fair share of defense spending. The Trump administration also missed its promised deadline to reunite dozens of migrant families. A natural gas leak in Sun Prairie, Wisc., turned deadly when an explosion erupted for several hours. Brett Kavanaugh, the president's pick for the open Supreme Court seat, met on Capitol Hill with the vice president and senators yesterday. The NFL Players Association is challenging the anti-kneeling policy, which requires players to remain in the locker room if they choose to protest the national anthem. Hurricane Chris makes its way up the East Coast, but shouldn't make a major impact on land. Cheddar Big News' Jill Wagner gives us the details.
A Single Goal Sent France to the World Cup Final
France kicked Belgium out of the championship tournament on Tuesday. Some of the team's success so far can be attributed to its coach, Didier Deschamps, who captained the 1998 title-winning team and can convey that experience to his players, says Jeffrey Marcus, publisher of The Banter.
Does Croatia Have What it Takes to Beat England?
After Croatia's long-fought match against Russia on Saturday, the team may not have the stamina to beat England this week. "Croatia's had to play two very long 120-minute games followed by penalty shootouts," says Mike Murphy, deputy editor at Quartz. "That'll work in England's favor."
Load More