These are the headlines you Need2Know:
* **Vatican Responds to Allegations of Abuse in Catholic Church:**
The Vatican responded Thursday to a Pennsylvania grand jury report on sex abuse by priests ー and subsequent cover-ups. In a statement, the Vatican said Pope Francis was "on the victims' side," and the Church “must learn hard lessons from its past.” The devastating report released this week concluded that 300 priests may have abused thousands of children over seven decades.
For more, [click here](https://www.cbsnews.com/news/vatican-condemns-sex-abuse-described-in-pennsylvania-grand-jury-report-2018-08-16/).
* **Deliberation Continues in Manafort Trial:**
The jury will convene Friday for the second day of deliberation in the trial of President Trump's former campaign chair, Paul Manafort. The jury took a recess after submitting four questions to U.S. District Judge T.S. Ellis III, including one asking him to define “reasonable doubt." Even if Manafort is acquitted of the charges, he will face another trial later this year. For more, [click here](https://www.washingtonpost.com/local/jury-begins-deliberations-in-paul-manaforts-tax--and-bank-fraud-trial/2018/08/16/d2b0f486-a170-11e8-8e87-c869fe70a721_story.html?utm_term=.08842ccc3912).
* **Rest in Peace, Queen of Soul:**
Aretha Franklin died Thursday from pancreatic cancer. The Queen of Soul, a Grammy-award winning singer and civil-rights activist whose most popular hits include “Respect” and “A Natural Woman,” was 76. Read Rolling Stone's obituary for Franklin [here](https://www.rollingstone.com/music/music-news/aretha-franklin-queen-of-soul-dead-at-76-119453/).
* **Trump Goes After Big Pharma**
The President called Thursday for the Justice Department to pursue lawsuits against drug companies for deceitful marketing of opioids. The Centers for Disease Control reported on Wednesday that 72,000 Americans died of drug overdoses last year ー a 10 percent increase from 2016. For more, [click here](https://www.usatoday.com/story/news/politics/2018/08/16/donald-trump-opioid-makers-could-face-federal-lawsuit/1008957002/).
Cheddar's Jill Wagner gets into the latest.
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Instagram CEO Adam Mosseri faced a bipartisan Congressional grilling this week as the Senate inquired about safety practices for protecting the mental wellbeing of young people on the platform. Sen. Marsha Blackburn (R-Tenn.) joined Cheddar to talk about the hearing and how she was disappointed in Instagram coming unprepared with relevant information or documents. Blackburn also offered concern that the platform could continue with building a kids-only version despite having drawn significant opposition from the public.
The Great Resignation has shown some signs of slowing in October with the number of those who quit their jobs falling by 4.7 percent to 4.16 million. This comes as worker strikes and calls for unionization ramp up. Jane Oates, president at WorkingNation joined Cheddar's "Opening Bell" to discuss the implications.
U.S. markets opened lower despite positive jobs data, which saw weekly claims drop to a 52-year low. Kevin Nicholson, Co-CIO Global Fixed Income, RiverFront Investment Group joined Cheddar's Opening Bell to discuss the labor market, inflation, and the impact of the Omicron variant on global markets.
A packed Thursday pod: Carlo and Baker cover the latest developments in the Ghislaine Maxwell, Jussie Smollett and Elizabeth Holmes trials. Plus, Dems are losing the Hispanic vote, Boris Johnson in trouble again, and is it possible that Adele has peaked?
Jim Bruderman, Vice Chairman at 1879 Advisors, joins Cheddar News' Closing Bell, where he says investors experienced a 'panic attack' last week with the spread of the Omicron variant and the Fed's tapering plans. As a result, he says we're now seeing stocks climb due to a growing comfort level toward both developments.
Adam Mosseri, head of Instagram, faced withering questions on Capitol Hill about the reports the social media app was aware of the severe mental health impacts it was having on teenage girls. Karen Kornbluh, the director of digital innovation and democracy for the German Marshall Fund, joined Cheddar to discuss the rare show of bipartisan outrage on display at the Senate hearing. "The senators came really loaded for bear on both sides of the aisle," she said. Kornbluh explained how senators like Richard Blumenthal (D-Conn.) set up fake Instagram accounts with teen girl profiles in order to research the effects firsthand.
The Biden administration will not send an official U.S. delegation to the 2022 Winter Olympics in Beijing as a statement against China's "ongoing genocide and crimes against humanity in Xinjiang." Weifeng Zhong, senior research fellow at George Mason University's Mercatus Center, joins Cheddar News to discuss the boycott.
