These are the headlines you Need 2 Know.
* **Two Killed in Florida Shooting:**
A 24-year-old gunman opened fire Sunday at a Madden video game competition in Florida, killing two and injuring 11 before turning the gun on himself. The shooter, David Katz, won the tournament in 2017 under the pseudonym "Bread." Police still haven’t determined a motive. For the latest [click here](https://www.cnn.com/2018/08/26/us/jacksonville-madden-shooting/index.html).
* **Remembering McCain:**
The late Arizona Senator died from cancer on Sunday. He was 81. The former Vietnam vet, prisoner of war, and six-term Republican senator was known for collaborating with lawmakers on both sides of the aisle. Here's how Republicans and Democrats are [remembering the former presidential candidate](http://www.time.com/5377616/john-mccain-political-tributes/).
* **Pope Francis Accused of Covering Up Abuse:**
According to an explicit, 11-page letter published Sunday, Pope Francis knew about sex abuse allegations made against ex-Cardinal McCarrick for years. The letter, penned by the Vatican’s former ambassador to the U.S., calls for the Pope's resignation and said he covered up the abuse and even elevated McCarrick's status.
[Read the latest, here](https://www.nbcnews.com/news/world/explosive-letter-claims-pope-francis-helped-cover-cardinal-mccarick-sex-n903936).
* **Hurricane Lane Flooding Ahead:**
The storm drenched Hawaii with more than 46 inches of rain last week, and officials say the worst is over. But Lane is now considered a tropical storm, and forecasters warn that serious flooding is a real possibility. For the latest [click here](https://www.newsweek.com/hurricane-lane-latest-hawaii-storm-warnings-lifted-flooding-still-major-1090945).
Cheddar's Jill Wagner gets into the latest.
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Instagram CEO Adam Mosseri faced a bipartisan Congressional grilling this week as the Senate inquired about safety practices for protecting the mental wellbeing of young people on the platform. Sen. Marsha Blackburn (R-Tenn.) joined Cheddar to talk about the hearing and how she was disappointed in Instagram coming unprepared with relevant information or documents. Blackburn also offered concern that the platform could continue with building a kids-only version despite having drawn significant opposition from the public.
The Great Resignation has shown some signs of slowing in October with the number of those who quit their jobs falling by 4.7 percent to 4.16 million. This comes as worker strikes and calls for unionization ramp up. Jane Oates, president at WorkingNation joined Cheddar's "Opening Bell" to discuss the implications.
U.S. markets opened lower despite positive jobs data, which saw weekly claims drop to a 52-year low. Kevin Nicholson, Co-CIO Global Fixed Income, RiverFront Investment Group joined Cheddar's Opening Bell to discuss the labor market, inflation, and the impact of the Omicron variant on global markets.
A packed Thursday pod: Carlo and Baker cover the latest developments in the Ghislaine Maxwell, Jussie Smollett and Elizabeth Holmes trials. Plus, Dems are losing the Hispanic vote, Boris Johnson in trouble again, and is it possible that Adele has peaked?
Jim Bruderman, Vice Chairman at 1879 Advisors, joins Cheddar News' Closing Bell, where he says investors experienced a 'panic attack' last week with the spread of the Omicron variant and the Fed's tapering plans. As a result, he says we're now seeing stocks climb due to a growing comfort level toward both developments.
Adam Mosseri, head of Instagram, faced withering questions on Capitol Hill about the reports the social media app was aware of the severe mental health impacts it was having on teenage girls. Karen Kornbluh, the director of digital innovation and democracy for the German Marshall Fund, joined Cheddar to discuss the rare show of bipartisan outrage on display at the Senate hearing. "The senators came really loaded for bear on both sides of the aisle," she said. Kornbluh explained how senators like Richard Blumenthal (D-Conn.) set up fake Instagram accounts with teen girl profiles in order to research the effects firsthand.
The Biden administration will not send an official U.S. delegation to the 2022 Winter Olympics in Beijing as a statement against China's "ongoing genocide and crimes against humanity in Xinjiang." Weifeng Zhong, senior research fellow at George Mason University's Mercatus Center, joins Cheddar News to discuss the boycott.