*By Christian Smith*
After an overdose earlier this week, Demi Lovato's life was reportedly saved by Narcan, a nasal administrator of naloxone that counteracts the effects of opioids. When administered quicklyーthrough either nasal mist or injectionーnaloxone can temporarily halt an overdose, allowing EMTs enough time to respond. The medication is available without a prescription in 49 states, and the generic version costs about $20 per dose.
But all merits aside, is the drug's accessibility enabling addicts to push their limits?
Dr. Roger Crystal, the lead inventor of Narcan and CEO of Opiant Pharmaceuticals, says there's little evidence to support that concern.
"Addiction like any kind of chronic disease is something you can control using better medication, but ultimately you can't cure," Crystal told Cheddar. "To think about an opioid addict behaving rationally and saying, 'well because I have access to Narcan I'll shoot more heroin, inject more heroin' there's no proof for that whatsoever."
Naloxone is considered some of the best ammunition on the front lines of America's growing opioid epidemic. A reported 2 million Americans have an addition to opioidsーand the number isn't going down. U.S. Surgeon General Jerome Adams [issued an advisory](https://www.surgeongeneral.gov/priorities/opioid-overdose-prevention/naloxone-advisory.html) in April urging anyoneーand their close family and friendsーwho uses painkillers, heroin, fentanyl, or other opioids to carry naloxone in case of an emergency.
Crystal isn't stopping at Narcan: he told Cheddar he's also developing a heroin vaccine, suggesting the inventor has lofty ambitions for the future of overdose prevention.
Although Crystal may be aware of lingering ethical concerns, he doesn't think they dwarf his mission. After all, Lovato has him to thank.
"Putting it in the hands of everyone and anyone is critical," Crystal said.
For more on this story, [click here](https://cheddar.com/videos/how-one-pharmaceutical-company-is-fighting-the-opioid-epidemic).
For the first time microplastics have been found deep in the lungs of living humans. The trace materials potentially came from everyday items such as plastic bottles and bags. Dr. Jessica Shepherd, the chief medical officer at Verywell Health, joined Cheddar News to talk about the report's findings and to discuss the possible risks people might face. "The study’s most important part is we need to decrease our pollution, and we need to think about different ways to consume outside of plastic," she said.
An estimated five billion people lack access to affordable and safe surgical care around the world. For World Health Day, Cheddar News spoke with Kristie Magee Porcaro of Operation Smile, a nonprofit organization assisting with cleft lip and palate surgeries, about how they work to better it around the globe.
There has been notable disagreement in the medical community about a fourth COVID-19 vaccine dose. The FDA last week authorized a second booster dose for older and immunocompromised individuals, as some agency officials did not support the idea. The FDA made the decision without meeting with its advisory committee, as it had ahead of its recommendations on the previous COVID-19 vaccine doses.
The CDC followed in the footsteps of the FDA and authorized a fourth dose as well. Reports say the agency also did not discuss the move with its own advisory team of vaccine experts. Now, a growing number of doctors are speaking out against the decisions - leaving people confused about whether they should get another vaccine dose. Dr. Julie Morita, a member of the CDC's advisory committee to the director, and the executive vice president of the Robert Wood Johnson Foundation, joins Cheddar News' Closing Bell to discuss.
Talmon Marco, CEO of H2Pro, joins Cheddar Innovates to discuss how to bring environmentally friendly hydrogen to scale, and what this means for hydrogen's many use cases.
Catching you up on what you need to know on April 7, 2022, with updates on Ukraine urging NATO for military aid for their war with Russia, the SEC investigating Amazon, microplastics being found deep inside human lungs for the first time, and more.
Patients who have grown frustrated with lingering COVID-19 symptoms and unanswered questions are now not only the subjects of "long covid" research, but also partners in pushing this research forward. Harlan Krumholz, professor of medicine at Yale University, joins Cheddar News to discuss.
A record number of tornadoes were observed in March, topping the previous record set last year. Cheddar News speaks with NOAA’s Harold Brooks about what the implications are of an early tornado season.
Catching you up on what you need to know on April 6, 2022, with updates on the FDA’s meeting to discuss a second COVID booster shot, more on the war in Ukraine, tornadoes on the Gulf coast, a third suspect arrested in connection to the mass shooting in California, Darwin’s lost notebooks mysteriously returned, and more.
Two of naturalist Charles Darwin’s notebooks that were reported stolen from Cambridge University have been returned, two decades after they disappeared.
