*By Christian Smith*
After an overdose earlier this week, Demi Lovato's life was reportedly saved by Narcan, a nasal administrator of naloxone that counteracts the effects of opioids. When administered quicklyーthrough either nasal mist or injectionーnaloxone can temporarily halt an overdose, allowing EMTs enough time to respond. The medication is available without a prescription in 49 states, and the generic version costs about $20 per dose.
But all merits aside, is the drug's accessibility enabling addicts to push their limits?
Dr. Roger Crystal, the lead inventor of Narcan and CEO of Opiant Pharmaceuticals, says there's little evidence to support that concern.
"Addiction like any kind of chronic disease is something you can control using better medication, but ultimately you can't cure," Crystal told Cheddar. "To think about an opioid addict behaving rationally and saying, 'well because I have access to Narcan I'll shoot more heroin, inject more heroin' there's no proof for that whatsoever."
Naloxone is considered some of the best ammunition on the front lines of America's growing opioid epidemic. A reported 2 million Americans have an addition to opioidsーand the number isn't going down. U.S. Surgeon General Jerome Adams [issued an advisory](https://www.surgeongeneral.gov/priorities/opioid-overdose-prevention/naloxone-advisory.html) in April urging anyoneーand their close family and friendsーwho uses painkillers, heroin, fentanyl, or other opioids to carry naloxone in case of an emergency.
Crystal isn't stopping at Narcan: he told Cheddar he's also developing a heroin vaccine, suggesting the inventor has lofty ambitions for the future of overdose prevention.
Although Crystal may be aware of lingering ethical concerns, he doesn't think they dwarf his mission. After all, Lovato has him to thank.
"Putting it in the hands of everyone and anyone is critical," Crystal said.
For more on this story, [click here](https://cheddar.com/videos/how-one-pharmaceutical-company-is-fighting-the-opioid-epidemic).
Carlo and Baker cover the big races to watch on this off-cycle Election Day, the concrete pledges starting to come out of COP26, Jeffrey Epstein keeps causing CEOs to lose their jobs, and Ryan Murphy's TV hit that wasn't.
The UN climate change conference kicked off on Sunday with about 120 world leaders and delegates gathering in Glasgow, Scotland this week, as experts continue to warn about the harms of heightened emissions and the effects on climate change. The topic of ESG investing is expected to be a top priority at the summit. Jefferies global head of ESG and sustainability research Aniket Shah joined Cheddar News' Closing Bell to discuss.
Christian Kroll, CEO of Ecosia, joins 'Fast Forward' to discuss how Ecosia uses its ad revenue to plant trees, and what the company plans to do after launching a $405 million venture capital fund focused on combating the climate crisis.
Dr. Ashley McClure, co-founder of Climate Health Now, joins 'Fast Forward' to discuss why the climate crisis is the greatest threat to humanity and health, and measures we need to take to reverse course.
Clinical research company Medable has secured $304 million in Series D funding, marking its fourth round since 2020, giving the firm a valuation of just over $2 billion. Dr. Michelle Longmire, CEO and Co-founder, Medable joined Cheddar's Opening Bell to discuss the future of the company.
The National Hurricane Center announced that the list of storm names in 2021 has been exhausted as one of the most active hurricane seasons in history continues to stir in the Atlantic Ocean. Subtropical Storm Wanda marks only the third time in history (last year being the second) that all the names were used in a single season.
Astronomers at NASA have located what could be the first exoplanet not only outside of the solar system but outside of our own galaxy in the Messier 51 (or the Whirlpool Galaxy), 28 million light-years away. It could take astronomers up to 70 years to see if the planet passes in front of its star to verify the find.
Even with pandemic lockdowns, greenhouse gas levels reached new highs in 2020, according to the World Meteorological Organization. This report comes just a week ahead of the United Nations Climate Change Conference, otherwise known as Cop26. Shannon Osaka, climate policy and solutions reporter at Grist, joined Cheddar's Between Bells to discuss.
Oatly Chief Sustainability Officer, Ashley Allen joins Cheddar News to talk about food waste and hows its been left off the table in the upcoming COP26 agenda. Ashley will be on the ground at COP26 and advocating for this conversation to get the attention it deserves.
Carlo's flying solo today, talking COP26 and climate change, another racially charged trial gets underway, SCOTUS takes on abortion and a stunning rise in traffic deaths points to a bigger societal breakdown sparked by the pandemic.
