*By Christian Smith*
After an overdose earlier this week, Demi Lovato's life was reportedly saved by Narcan, a nasal administrator of naloxone that counteracts the effects of opioids. When administered quicklyーthrough either nasal mist or injectionーnaloxone can temporarily halt an overdose, allowing EMTs enough time to respond. The medication is available without a prescription in 49 states, and the generic version costs about $20 per dose.
But all merits aside, is the drug's accessibility enabling addicts to push their limits?
Dr. Roger Crystal, the lead inventor of Narcan and CEO of Opiant Pharmaceuticals, says there's little evidence to support that concern.
"Addiction like any kind of chronic disease is something you can control using better medication, but ultimately you can't cure," Crystal told Cheddar. "To think about an opioid addict behaving rationally and saying, 'well because I have access to Narcan I'll shoot more heroin, inject more heroin' there's no proof for that whatsoever."
Naloxone is considered some of the best ammunition on the front lines of America's growing opioid epidemic. A reported 2 million Americans have an addition to opioidsーand the number isn't going down. U.S. Surgeon General Jerome Adams [issued an advisory](https://www.surgeongeneral.gov/priorities/opioid-overdose-prevention/naloxone-advisory.html) in April urging anyoneーand their close family and friendsーwho uses painkillers, heroin, fentanyl, or other opioids to carry naloxone in case of an emergency.
Crystal isn't stopping at Narcan: he told Cheddar he's also developing a heroin vaccine, suggesting the inventor has lofty ambitions for the future of overdose prevention.
Although Crystal may be aware of lingering ethical concerns, he doesn't think they dwarf his mission. After all, Lovato has him to thank.
"Putting it in the hands of everyone and anyone is critical," Crystal said.
For more on this story, [click here](https://cheddar.com/videos/how-one-pharmaceutical-company-is-fighting-the-opioid-epidemic).
The two-week COP26 climate conference has now ended with leaders reaching a deal, but so far the deal is getting mixed reviews from climate experts across the globe. Chloe Demrovsky, president and CEO of Disaster Recovery Institute International, explains that while the agreement is a step forward in some ways, the world still has much more to work on in order to keep warming to below 2 degrees Celsius.
Jill and Carlo cover the latest with the infrastructure bill, the growing state rebellion over boosters, Trump's dereliction of duty on the pandemic, Taylor Swift's reign of cultural domination and more.
Aurora Cannabis CEO Miguel Martin joins Cheddar News' Closing Bell to discuss the company's latest earnings results, how it will achieve positive EBITDA by 2023, and the state of the cannabis industry amid potential U.S. federal legalization.
Moderna is defending its COVID-19 vaccine after a study found an increase in reports of myocarditis, which is an inflammation of the heart, in males ages 12 to 29 — about 13.3 cases in every 100,000 subjects. The pharmaceutical giant said the benefits of the vaccine outweigh the risk of the possible negative side effect.
The parent company of North Face, Vans and Supreme, VF Corp, released its fourth annual "Made for Change" sustainability and responsibility report. It details the company's ongoing efforts to tackle social and climate related issues. This comes as climate experts continue to warn about the dangers of fast fashion and its impact on global CO2 emissions. Sean Cady, Vice President of Global Sustainability, Responsibility and Trade at VF Corporation, joins Cheddar News to discuss.
A jam-packed Freitag pod with Carlo and Baker: new Covid hotspots, Kyle Rittenhouse trial, Belarus making trouble for Europe, red-hot housing market, and how to manage a PR crisis the right way.
As the UN climate conference is set to wrap this week, we take a look at pledges that world leaders have signed onto so far and the most important developments to come out of COP26. Sandeep Pai, Senior Research Lead at the Just Transition Initiative, joins Cheddar Climate to discuss the most important global initiatives and biggest pledges made by global leaders, and whether or not they can truly make an impact if two of the world's biggest economies, China and Russia, did not attend and are not fully committed to major climate initiatives.
A group of health experts from around the world is issuing a dire warning about the climate crisis, saying that climate change is the greatest global health threat facing the world this century and is set to become the 'defining narrative of human health.' The Lancet medical journal stated that warning in its annual report, along with a policy brief for the United States detailing actions the country can take to stop millions of unnecessary deaths. Director of Climate for Health at EcoAmerica Rebecca Rehr joined Cheddar Climate to discuss.
The COP26 summit in Scotland is in its final days, and the U.N. has just released a draft of an agreement for more than 200 world leaders to sign on Friday. The draft urges nations to set more aggressive goals in cutting emissions, while also calling for coal to be phased out. Chloe Demrovsky, President and CEO of Disaster Recovery Institute International, joins Cheddar News to discuss this agreement.
SpaceX and NASA have collaborated on another successful launch sending four astronauts to the international space station. The international crew will stay in orbit aboard the ISS for six months.
