*By Christian Smith*
After an overdose earlier this week, Demi Lovato's life was reportedly saved by Narcan, a nasal administrator of naloxone that counteracts the effects of opioids. When administered quicklyーthrough either nasal mist or injectionーnaloxone can temporarily halt an overdose, allowing EMTs enough time to respond. The medication is available without a prescription in 49 states, and the generic version costs about $20 per dose.
But all merits aside, is the drug's accessibility enabling addicts to push their limits?
Dr. Roger Crystal, the lead inventor of Narcan and CEO of Opiant Pharmaceuticals, says there's little evidence to support that concern.
"Addiction like any kind of chronic disease is something you can control using better medication, but ultimately you can't cure," Crystal told Cheddar. "To think about an opioid addict behaving rationally and saying, 'well because I have access to Narcan I'll shoot more heroin, inject more heroin' there's no proof for that whatsoever."
Naloxone is considered some of the best ammunition on the front lines of America's growing opioid epidemic. A reported 2 million Americans have an addition to opioidsーand the number isn't going down. U.S. Surgeon General Jerome Adams [issued an advisory](https://www.surgeongeneral.gov/priorities/opioid-overdose-prevention/naloxone-advisory.html) in April urging anyoneーand their close family and friendsーwho uses painkillers, heroin, fentanyl, or other opioids to carry naloxone in case of an emergency.
Crystal isn't stopping at Narcan: he told Cheddar he's also developing a heroin vaccine, suggesting the inventor has lofty ambitions for the future of overdose prevention.
Although Crystal may be aware of lingering ethical concerns, he doesn't think they dwarf his mission. After all, Lovato has him to thank.
"Putting it in the hands of everyone and anyone is critical," Crystal said.
For more on this story, [click here](https://cheddar.com/videos/how-one-pharmaceutical-company-is-fighting-the-opioid-epidemic).
Experts say that at some point next year, the pandemic will officially drop its pandemic status, becoming endemic. While this is a milestone to acknowledge, it does not mean we're free of infections, illnesses, and deaths. Dr. Rajeev Fernando, infectious disease specialist, Beth Israel Hospital and fellow, joins Cheddar News' Closing Bell to discuss.
Chicago-based Internist Dr. Vivek Cherian joined Wake Up With Cheddar to break down the unprecedented surge in U.S. COVID-19 as many prepare to celebrate the new year.
Dr. Soumi Eachempati, co-founder and CEO of Cleared4 and former professor of surgery and public health at Weill Cornell Medical College, joined Cheddar to breakdown what people should know about the recently FDA-approved emergency use of Merck and Pfizer's COVID-19 treatment pills. He noted that not only do people need to be aware of other medications they are taking that could cause adverse effects if coupled with COVID-19 pill treatments, he also talked about the intense in-take regiment. "The Merck pills are actually about 40 pills over five days. The Pfizer ones are three pills over five days, so people have to be prepared for that because it is a lot of pills you'll have to take to get full value from these drugs," Eachempati told Cheddar.
Twitter is exploding with a new meme after the CDC revised its Covid-19 guidelines, shortening the recommended isolation period to five days instead of 10 for when you test positive and are asymptomatic. The change came amid a skyrocketing surge of new cases is the U.S. due to the Omicron variant, drawing criticism from experts and Twitter --with users claiming the government agency is giving funny advise on a variety of issues. But what does the meme say about the public’s trust in the agency? Cheddar News speaks with political strategist Hastie Afkhami.
The list of questions should be getting shorter as we enter the pandemic's third year, but that isn't the case. There's another question to add to that list: is the U.S. doing enough to track the virus and its variants? Lawrence Gostin, faculty director of the O'Neill Institute for national and global health law at Georgetown University, joins Cheddar News.
As we prepare to ring in the new year, COVID cases are hitting an all-time high. Dr. Anthony Fauci has said the safest way to celebrate would be a small gathering with vaccinated family members only... far from the large, flashy parties from a few years ago. Dr. Christina Johns, senior medical advisor at PM Pediatrics, joins Cheddar News to discuss how to celebrate safely.
