Would you volunteer to be deliberately infected with COVID-19? It's a question some people are seriously considering. In an effort to speed up the development of a vaccine, 1 Day Sooner is asking volunteers to sign up for human challenge trials that will expose them to the virus in an effort to study the disease and develop a cure.
Josh Morrison, the co-founder of 1 Day Sooner, told Cheddar Wednesday that these human challenges have been used to study other diseases in the past, including malaria, typhoid, and cholera.
"The drug Tamiflu, for example, was developed with challenge trials, as well as the malaria vaccine RTS,S that's being deployed in Africa right now," he said. "You can find out much more quickly whether a vaccine might work, than a traditional trial which might have thousands or even tens of thousands of volunteers."
The National Institutes of Health and the World Health Organization have shown interest in the human challenge trials, according to Morrison. The WHO recently published an ethics report to which the 1 Day Sooner team offered suggestions, though they were not accepted for the publication.
Morrison said that there has been growing interest in the trials, adding, "It's not universal acclaim or an immediate 'we need challenge trials right away from every possible corner,' but the message today is immensely different, immensely more positive than what the public message was a month ago."
He acknowledged that the risk of injecting people with COVID-19 could be deadly, but he said he believes that the potential value of finding a vaccine from these challenges is worth it.
"If you look at the risks of getting COVID-19 for the young, healthy group that would participate in challenge trials, they're roughly on a par with childbirth or with kidney donation. So, again, significant risk and we're not understating that, but these are risks that we commonly allow people to accept normally, and given the tremendous possible value we think it's worth accepting them in this case," the 1 Day Sooner co-founder said.
Cheddar's J.D. Durkin caught up with the head of NASA Bill Nelson, a former senator, who feels one thing that seems less rancorous on Capitol Hill these days is the work of the space agency.
Catching you up on what you need to know on April 22, 2022, with updates on a new Ukraine aid package, a new missile test by Russia, DOJ announcement of $150 Million in COVID-related fraud, the Florida senate supports Gov. DeSantis in stripping Disney of its special tax district, and more.
Scientists say a U.K. patient with a severely weakened immune system had COVID-19 for almost a year and a half. The case underscores the importance of protecting vulnerable people from the coronavirus.
Cheddar's Lawrence Banton speaks with entrepreneurs leading the way on textile and clothing recycling in an effort to help stem waste in fashion amid the climate crisis.
The FDA just approved a first-of-its-kind treatment for individuals with blood cancer that has proven results of 5-year survival rates. Christi Shaw, CEO of Kite, a Gilead company, joins Cheddar Innovates to discuss how this treatment works and compares to others currently on the market.
Dr. Neta Lavon, CTO and VP of R&D at Aleph Farms, joins Cheddar Innovates to discuss how the team sent cow cells to space to further research the production of meat in space, and why developing cultivated meat is so critical to the future of space travel.
Catching you up on what you need to know on April 21, 2022, with President Biden set to announce more security assistance funding to Ukraine, polls showing a majority of Americans in favor of transit mask mandates, rapper A$AP Rocky's arrest, and more.
Epidemiologist Dr. Eric Feigl-Ding joined Closing Bell to explain why ending the travel mask mandates could put the U.S. in a bad position in the coming months as new COVID-19 variants threaten to cause another spike in cases.
Laurence Tribe, a professor of constitutional law at Harvard University, joined Cheddar News to talk about the legal underpinnings of the ruling to lift the federal travel mask mandate. "Judge Mizelle decided that she would issue a nationwide injunction, which she and other conservatives have criticized in the past," he said. "That didn't stop her from doing it this time. She did it by just wiping away the CDC's rule, and she did it, have to say, in an opinion that was, well, I'll be honest, really stupid."
