Would you volunteer to be deliberately infected with COVID-19? It's a question some people are seriously considering. In an effort to speed up the development of a vaccine, 1 Day Sooner is asking volunteers to sign up for human challenge trials that will expose them to the virus in an effort to study the disease and develop a cure.
Josh Morrison, the co-founder of 1 Day Sooner, told Cheddar Wednesday that these human challenges have been used to study other diseases in the past, including malaria, typhoid, and cholera.
"The drug Tamiflu, for example, was developed with challenge trials, as well as the malaria vaccine RTS,S that's being deployed in Africa right now," he said. "You can find out much more quickly whether a vaccine might work, than a traditional trial which might have thousands or even tens of thousands of volunteers."
The National Institutes of Health and the World Health Organization have shown interest in the human challenge trials, according to Morrison. The WHO recently published an ethics report to which the 1 Day Sooner team offered suggestions, though they were not accepted for the publication.
Morrison said that there has been growing interest in the trials, adding, "It's not universal acclaim or an immediate 'we need challenge trials right away from every possible corner,' but the message today is immensely different, immensely more positive than what the public message was a month ago."
He acknowledged that the risk of injecting people with COVID-19 could be deadly, but he said he believes that the potential value of finding a vaccine from these challenges is worth it.
"If you look at the risks of getting COVID-19 for the young, healthy group that would participate in challenge trials, they're roughly on a par with childbirth or with kidney donation. So, again, significant risk and we're not understating that, but these are risks that we commonly allow people to accept normally, and given the tremendous possible value we think it's worth accepting them in this case," the 1 Day Sooner co-founder said.
The 2022 County Health Rankings largely found that the pandemic worsened the burdens faced by women, people of color, and in low income brackets. Cheddar News speaks with Sheri Johnson, co-director of County Health Rankings and Roadmaps who breaks down the details.
With National Infertility Awareness Week underway, the fertility and family-building benefits provider for employers, Kindbody, is looking to make a full suite of treatments and care accessible — including for LGBTQ+ patients. Founder and chairwoman Gina Bartasi joined Cheddar's Opening Bell to talk about the importance of infertility awareness, what role employers play in offering benefits, and how to remove the stigma around the fertility conversation. "We have to talk about the patient holistically, not just fertility services, but what can we do from a mental health standpoint to support patients," she said. "Most patients talk about fertility being more stressful than divorce, infertility being more prevalent than cancer or diabetes. So it is our mission, remains our mission, to elevate awareness around infertility, not just [during] National Infertility Awareness Week."
New York City’s geography makes it particularly at risk to the impacts of climate change - like rising seas and subsequent flooding. The city has already experienced the effects of increasingly severe weather. In response, the city is building a plan to protect itself, from flood walls, to levees, to redesigning its coast.
With mask mandates lifted across various parts of the country, healthy indoor air quality in public spaces is more crucial than ever before. According to the CDC, proper ventilation, in addition to other preventative measures, is instrumental to preventing the rapid spread of covid-19 indoors. As the push for higher air quality ramps up, AtmosAir is providing a high-tech solution for cleaner, greener air indoors. Steve Levine, CEO, AtmosAir, joined Cheddar’s Opening Bell to discuss.
Catching you up on what you need to know on April 27, 2022, with Tesla stocks absorbing an initial hit following Elon Musk's purchase of Twitter, Russia pausing its natural gas supplies to Poland and Bulgaria, NASA's SpaceX Crew-4 mission taking off, and more.
New Mexico is under a state of emergency after flames scorched across 84 square miles. Strong winds fueled 20 wildfires, destroying hundreds of buildings in the state this weekend. New Mexico is just one of several states across the southwest facing severe wildfires. James McMullen, retired California state fire marshal and forensic fire expert, joins Cheddar News to discuss.
SpoonTEK is an eating utensil that uses new technology to enhance flavors. Co-founders Ken and Cameron Davidov join Cheddar News to explain how the high-tech silverware can not only boost taste but also the health of its user.
Tim Brown, research professor at Desert Research Institute and director at the Western Regional Climate Center, joins Cheddar News to discuss the environmental impact of recent wildfires.
Vice President Kamala Harris tested positive for COVID-19 on Tuesday, the White House announced. That's underscoring the persistence of the highly contagious virus even as the U.S. eases restrictions in a bid to revert to pre-pandemic normalcy.
