Would you volunteer to be deliberately infected with COVID-19? It's a question some people are seriously considering. In an effort to speed up the development of a vaccine, 1 Day Sooner is asking volunteers to sign up for human challenge trials that will expose them to the virus in an effort to study the disease and develop a cure.
Josh Morrison, the co-founder of 1 Day Sooner, told Cheddar Wednesday that these human challenges have been used to study other diseases in the past, including malaria, typhoid, and cholera.
"The drug Tamiflu, for example, was developed with challenge trials, as well as the malaria vaccine RTS,S that's being deployed in Africa right now," he said. "You can find out much more quickly whether a vaccine might work, than a traditional trial which might have thousands or even tens of thousands of volunteers."
The National Institutes of Health and the World Health Organization have shown interest in the human challenge trials, according to Morrison. The WHO recently published an ethics report to which the 1 Day Sooner team offered suggestions, though they were not accepted for the publication.
Morrison said that there has been growing interest in the trials, adding, "It's not universal acclaim or an immediate 'we need challenge trials right away from every possible corner,' but the message today is immensely different, immensely more positive than what the public message was a month ago."
He acknowledged that the risk of injecting people with COVID-19 could be deadly, but he said he believes that the potential value of finding a vaccine from these challenges is worth it.
"If you look at the risks of getting COVID-19 for the young, healthy group that would participate in challenge trials, they're roughly on a par with childbirth or with kidney donation. So, again, significant risk and we're not understating that, but these are risks that we commonly allow people to accept normally, and given the tremendous possible value we think it's worth accepting them in this case," the 1 Day Sooner co-founder said.
Carlo and Baker cover the big races to watch on this off-cycle Election Day, the concrete pledges starting to come out of COP26, Jeffrey Epstein keeps causing CEOs to lose their jobs, and Ryan Murphy's TV hit that wasn't.
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Christian Kroll, CEO of Ecosia, joins 'Fast Forward' to discuss how Ecosia uses its ad revenue to plant trees, and what the company plans to do after launching a $405 million venture capital fund focused on combating the climate crisis.
Dr. Ashley McClure, co-founder of Climate Health Now, joins 'Fast Forward' to discuss why the climate crisis is the greatest threat to humanity and health, and measures we need to take to reverse course.
Clinical research company Medable has secured $304 million in Series D funding, marking its fourth round since 2020, giving the firm a valuation of just over $2 billion. Dr. Michelle Longmire, CEO and Co-founder, Medable joined Cheddar's Opening Bell to discuss the future of the company.
The National Hurricane Center announced that the list of storm names in 2021 has been exhausted as one of the most active hurricane seasons in history continues to stir in the Atlantic Ocean. Subtropical Storm Wanda marks only the third time in history (last year being the second) that all the names were used in a single season.
Astronomers at NASA have located what could be the first exoplanet not only outside of the solar system but outside of our own galaxy in the Messier 51 (or the Whirlpool Galaxy), 28 million light-years away. It could take astronomers up to 70 years to see if the planet passes in front of its star to verify the find.
Even with pandemic lockdowns, greenhouse gas levels reached new highs in 2020, according to the World Meteorological Organization. This report comes just a week ahead of the United Nations Climate Change Conference, otherwise known as Cop26. Shannon Osaka, climate policy and solutions reporter at Grist, joined Cheddar's Between Bells to discuss.
Oatly Chief Sustainability Officer, Ashley Allen joins Cheddar News to talk about food waste and hows its been left off the table in the upcoming COP26 agenda. Ashley will be on the ground at COP26 and advocating for this conversation to get the attention it deserves.
Carlo's flying solo today, talking COP26 and climate change, another racially charged trial gets underway, SCOTUS takes on abortion and a stunning rise in traffic deaths points to a bigger societal breakdown sparked by the pandemic.
