In this image from video provided by the University of Maryland School of Medicine, Lawrence Faucette, a pig heart transplant patient, works with a physical therapist at the school's hospital in Baltimore, Md., on Wednesday, Oct. 18, 2023. (Tom Jemski/University of Maryland School of Medicine via AP)
Lawrence Faucette was dying from heart failure and ineligible for a traditional heart transplant because of other health problems when doctors at the University of Maryland School of Medicine offered the highly experimental surgery.
In the first glimpse of Faucette provided since the Sept. 20 transplant, hospital video shows physical therapist Chris Wells urging him to smile while pushing through a pedaling exercise to regain his strength.
“That’s going to be tough but I’ll work it out,” Faucette, 58, replied, breathing heavily but giving a smile.
The Maryland team last year performed the world’s first transplant of a heart from a genetically altered pig into another dying man. David Bennett survived just two months before that heart failed, for reasons that aren’t completely clear although signs of a pig virus later were found inside the organ. Lessons from that first experiment led to changes before this second try, including better virus testing.
Attempts at animal-to-human organ transplants — called xenotransplants — have failed for decades, as people’s immune systems immediately destroyed the foreign tissue. Now scientists are trying again using pigs genetically modified to make their organs more humanlike.
In Friday’s hospital video, Faucette’s doctors said the pig heart has shown no sign of rejection.
“His heart is doing everything on its own,” said Dr. Muhammad Mohiuddin, the Maryland team’s cardiac xenotransplantation chief.
A hospital spokeswoman said Faucette, of Frederick, Maryland, has been able to stand and physical therapists are helping him gain strength needed to attempt walking.
Many scientists hope xenotransplants one day could compensate for the huge shortage of human organ donations. More than 100,000 people are on the nation’s list for a transplant, most awaiting kidneys, and thousands will die waiting.
A handful of scientific teams have tested pig kidneys and hearts in monkeys and in donated human bodies, hoping to learn enough for the Food and Drug Administration to allow formal xenotransplant studies.
The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.
A new study shows that Americans feel record levels of stress amid inflation and global uncertainty about the war in Ukraine. Cheddar News speaks with Lynn Bufka of the American Psychological Association about how to best put your worries aside.
Colgate-Palmolive is shedding light on the little-known fact that oral health is integral to overall health. The consumer products company will commit $100 million over five years to transform the way the world thinks about and addresses oral health. Maria Ryan, Chief Clinical Officer at Colgate-Palmolive, discusses why oral health is so vital to our physical and mental well-being.
Scientists say they have found the sunken wreck of polar explorer Ernest Shackleton’s ship Endurance, more than a century after it was lost to the Antarctic ice.
Researchers say a large spider native to East Asia that proliferated in Georgia last year could spread to much of the East Coast. The Joro spider’s golden web took over yards all over north Georgia in 2021, unnerving some residents.
News of Russian forces taking control of a Ukrainian after artillery bombardment of a nuclear power plant raised concerns this week. Nuclear policy expert and Quincy Institute Distinguished Fellow Joe Cirincione joined Cheddar News to discuss the implications for a potential disaster. “I’m with the director general of the IAEA, the International Atomic Energy Agency. He says that he is extremely concerned, and that this Russian attack is a severe risk and that Russia clearly violated the fundamental principle of preserving the integrity of nuclear power plants," Cirincione said.
Adam Battle, research assistant at University of Arizona's Lunar and Planetary Laboratory, joins Cheddar News to discuss space junk heading to the moon and if more should be done to prevent space junk in the future.
UN and Ukrainian officials say no radiation was released from a Russian attack at Europe’s biggest nuclear power plant in Ukraine and firefighters have extinguished a blaze at the facility..
Under the U.S. Renewable Fuel Standard (RFS), corn-based ethanol has been mixed into gasoline sold at pumps in the U.S. since 2005, when a policy was enacted aimed at reducing emissions. Corn-based ethanol had been thought to be a relatively greener energy source compared to other biofuels, but now, a new study published in the Proceedings of the National Academy of Sciences reports it may be actually worse for the climate than straight gasoline. Tyler Lark, an assistant scientist at the University of Wisconsin-Madison's Center for Sustainability, joined Cheddar News' Closing Bell and discussed the pushback against the study. "Essentially when you need to produce more corn to meet the demand for use as ethanol as fuel, farmers respond and they switch more crops like soybeans and wheat into corn," Lark said. "They also bring more land into production, so things that used to be pasture grassland, and both those activities are associated with increased greenhouse gas emissions."
Caroline Hickman, lecturer at University of Bath and psychosocial researcher on climate change, joins Cheddar News to discuss climate change's impact on mental health.
