While the coronavirus has impacted millions of Americans across the United States, it has hit the elderly population particularly hard. In fact, more than 40 percent of coronavirus deaths in the U.S. have been linked to long-term care facilities, according to a New York Times survey. In an effort to bring those numbers down, pharmaceutical company Eli Lilly, in partnership with the National Institutes of Health (NIH), has just launched a late-stage antibody treatment trial focusing on residents and staff at nursing homes.
"COVID-19 has had a devastating impact on nursing home residents," Lilly's chief scientific officer Daniel Skovronsky said in a statement. "We're working as fast as we can to create medicines that might stop the spread of the virus to these vulnerable individuals."
The trial is expected to enroll up to 2,400 participants who live or work at a facility and have recently been diagnosed with the disease. The trial will evaluate the safety and success of using LY-CoV555, a potent, neutralizing antibody that works against the spike protein of the novel coronavirus. The trial will look at whether a single dose of the antibody treatment reduces the rate of infection over four weeks as well as symptoms over eight weeks.
"The importance of these kinds of therapies for people like the elderly or immunocompromised is that they can provide the hope and the safety net that these people really need right now," said Andrew Adams, vice president of new therapeutic modalities & COVID-19 research at Eli Lilly, who is overseeing the trial. "I think people in those populations are really desperate and looking for something to help with the coronavirus."
Eli Lilly is taking its trial on the road with customized mobile research units that can travel directly to areas that are experiencing outbreaks.
"This is an interesting solution, to bring the medicine to these vulnerable patients," said Adams. "This lets us be flexible and move these trials around the country, tracking these trials as we come across them."
Adams said he is hoping Eli Lilly will have results on the efficacy of these antibodies in the fourth quarter of this year. Even if successful, though, he says research for a vaccine needs to continue.
"These have to be thought of as more of a bridge, where a vaccine provides long-term protection in terms of years of immunity, where we will provide hopefully in the range of months with these types of treatments. We hope this to be a short-term bridge to the long-term effective vaccination," he said.
Plant-based meat giant Beyond Meat's reign over the fast food world continues, as McDonald's announced that it is expanding its test of Beyond's McPlant burger, to nearly 600 restaurants, an increase from the eight that it's been testing in since November. This comes less than two weeks after Beyond Fried Chicken made its nationwide debut at KFC restaurants, the first time that plant based chicken has been widely distributed in a fast food capacity. Arun Sundaram, Senior Equity Analyst at CFRA Research explains why these latest collaborations may be proof that Beyond Meat products could slowly be becoming an unlikely staple in the fast food and chain restaurant world as consumers opt for more healthy food options.
BD Veritor is a variation of the at-home COVID test that uses a smartphone to interpret the results. The test is taken via a nose swab test strip that is then scanned by your phone’s camera with the result clearly displayed as positive or negative. James Walker, vice president of integrated diagnostics USA for BD, joined Cheddar to discuss how the test hopefully takes the "guesswork out of testing." Walker also went into what BD is doing to deal with the surging demand for at-home tests amid the omicron spread. "While we don't disclose how much we produce, we have capacity to manufacture up to 12 million rapid antigen tests per month and are delivering on our commitments to distributors and retailers," he said.
On this episode of Cheddar Innovates: Sidechef CEO breaks down how it's building a platform to make recipe shopping easy; Luum CEO explains the process of having a robot put on eyelash extensions; A look at Curiosity Stream's new original series, 'Evolve.'
Moderna launched a clinical trial of a COVID-19 booster shot specifically targeting the omicron variant. The first participant has already received a dose, and Moderna expects to enroll about 600 adults total, split between two groups. In the first group, participants will have previously received two doses of the Moderna vaccine, and in the second, participants will have received its booster. Dr. Paul Burton, chief medical officer at Moderna, joined Cheddar’s Opening Bell to discuss the trial, yearly boosters, and what lies ahead for the company.
With the 2022 Beijing Winter Olympics right around the corner, experts are warning that climate change is threatening not only the event but also the future of snow sports. Despite being the world's top polluter, China is hoping to use the event to demonstrate the country's commitment to fighting climate change, and pledging to host a "low carbon" games. Xubin Zeng, professor of hydrology and atmospheric sciences at the University of Arizona, joins Cheddar News.
New research is suggesting that giving extra cash to low-income mothers can actually influence the brain development of their infants. These findings provide the first rigorous evidence of how payments and monetary support can affect children in the early years of life. Authors of the study, Nathan Fox, professor in the department of human development at the University of Maryland, and Sonya Troller-Renfree, postdoctoral research associate at Teachers College at Columbia University, join Cheddar News to discuss.
Communities of color are disproportionately affected by climate change and continuously feel the impacts. Mark Magaña, founding president and CEO of Green Latinos joined All Hands to discuss.
